The simple answer: YES.
How? I recommend running into the sub then out to the Pro8 or Pro16 (or any other active speaker, to be honest).
- Connect your source (DJ controller, mixer, etc) to the Sub1/Sub2 via the line input 1 and/or 2.
- Connect XLR from line out 1 and/or 2, to jack (6.3mm) line input.
The Sub1/Sub2 Level Control does not affect the Line Outputs. The advantage here is you can adjust the subwoofer volume without affecting the rest of the system.
A real-world use for this might be during the earlier part of a wedding reception, you can have the sub turned down to almost zero, leaving the Pro8 or Pro16 to do all the work (dinner music, speeches etc). Then as your party picks up, you can turn the sub up through the night for extra “kick” when required.
Be aware – the Sub2 (and to a lesser degree the SUb1) can easily overpower the Pro16 and definitely the Pro8.